St. John’s Wort is one of the most well-known natural supplements used to treat depression. Some studies have found that it may be as effective as certain antidepressant medications in treating mild to moderate depression.
It is unknown if St. John’s Wort works to treat severe depression or treatment-resistant depression. Depending on the cause of your depression, St. John’s wort may also be harmful. Therefore, it is not a substitute for medical diagnosis and treatment. Also, studies on St. John’s Wort ended after 12 weeks of treatment, so the long-term side effects are currently unknown.
St. John’s Wort can be an effective option for mild to moderate depression. It can have serious side effects when taken with other medications, and it is dangerous to combine with antidepressant medications. Always consult a doctor before taking St. John’s Wort.
St. John’s Wort is designed to be taken by mouth as a capsule or tablet. Since taking St. John’s Wort as a supplement has only been studied for up to 12 weeks, the efficacy and side effects after 12 weeks are unknown.
Supplements are not regulated by the FDA like medications, so you should only purchase supplements from brands that have been evaluated for quality. Supplements are not FDA-approved to treat depression.